Description

(R)-(-)-1-Cyclohexylethyl Isothiocyanate is a chiral, non-racemic organic compound belonging to the isothiocyanate class, characterized by its specific stereochemistry at the chiral center. This compound matters as a versatile chiral building block and intermediate, enabling the synthesis of enantiomerically pure molecules critical for advanced research and development. It is needed by pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis, medicinal chemistry, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or metabolic diseases.
• Agrochemical Synthesis: Used in the preparation of enantiomerically pure herbicides, fungicides, and plant growth regulators, where specific stereochemistry can enhance efficacy and reduce environmental impact.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric catalysis, improving the selectivity and yield of synthetic transformations.
• Chemical Biology Research: Employed as a molecular probe or labeling agent due to the reactive isothiocyanate group, which can selectively modify proteins or other biomolecules for study.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of complex, chiral aroma chemicals where optical purity influences the sensory profile.
• Material Science: Can be utilized in the synthesis of chiral monomers for advanced polymers with specific optical or mechanical properties.

Basic Information

Product Name	(R)-(-)-1-Cyclohexylethyl Isothiocyanate
CAS No.	196402-21-8
Molecular Formula	C9H15NS
Molecular Weight	169.29 g/mol
Synonyms	(R)-1-Cyclohexylethyl isothiocyanate; (R)-(-)-1-Cyclohexylethyl isothiocyanate; (R)-1-(Isothiocyanatoethyl)cyclohexane; (R)-α-Methylcyclohexanemethyl isothiocyanate; (R)-1-Cyclohexyl-1-ethyl isothiocyanate; (1R)-1-Cyclohexylethyl isothiocyanate; (R)-(-)-1-Cyclohexylethyl mustard oil
EINECS	Contact for details

Quality Control

Our (R)-(-)-1-Cyclohexylethyl Isothiocyanate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and optical purity, meeting the stringent requirements for chiral intermediates. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.