Description

4-Amino-6-Methyl-8-(2-Deoxy-B-D-Ribofuranosyl)-7(8H)-Pteridone is a specialized nucleoside analog pteridone derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis of novel therapeutic agents and biochemical probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral, anticancer, and enzyme-targeting drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies and metabolic pathway analysis.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Analytical Standard: Employed as a high-purity calibrant in HPLC and LC-MS methods for quality control and pharmacokinetic studies.
• Antiviral Drug Development: Investigated for its potential activity against viral polymerases and reverse transcriptases.
• Enzyme Inhibitor Synthesis: Used to create analogs that target specific enzymes involved in nucleotide metabolism.

Basic Information

Product Name	4-Amino-6-Methyl-8-(2-Deoxy-B-D-Ribofuranosyl)-7(8H)-Pteridone
CAS No.	195442-55-8
Molecular Formula	C13H15N5O4
Molecular Weight	305.29 g/mol
Synonyms	8-(2-Deoxy-β-D-ribofuranosyl)-4-amino-6-methyl-7(8H)-pteridone; 4-Amino-6-methyl-8-(2-deoxy-β-D-ribofuranosyl)-7,8-dihydropteridine-2,7-dione; 2-Deoxy-β-D-ribofuranose pteridone derivative; 4-Amino-6-methylpteridine nucleoside; 7(8H)-Pteridone, 4-amino-6-methyl-8-(2-deoxy-β-D-ribofuranosyl)-; 195442-55-8
EINECS	Contact for details

Quality Control

Our 4-Amino-6-Methyl-8-(2-Deoxy-B-D-Ribofuranosyl)-7(8H)-Pteridone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.