Description

Fosfluconazole is a potent triazole antifungal agent, representing a significant advancement in the treatment of systemic fungal infections. Its primary value lies in its enhanced bioavailability and targeted action against a broad spectrum of pathogenic fungi, making it a critical intermediate for pharmaceutical synthesis. This compound is essential for manufacturers in the pharmaceutical industry developing advanced antifungal medications, as well as for research institutions conducting microbiological and pharmacological studies.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic precursor in the manufacture of advanced systemic antifungal drugs.
• Pharmaceutical Research & Development: Used in preclinical and clinical studies to develop new formulations and delivery systems for antifungal therapy.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.
• Veterinary Medicine: Potential application in the development of antifungal treatments for animal health.
• Microbiological Studies: Employed in research to study fungal resistance mechanisms and the efficacy of triazole compounds.

Basic Information

Product Name	Fosfluconazole
CAS No.	194798-83-9
Molecular Formula	C16H15F2N6O4P
Molecular Weight	424.30 g/mol
Synonyms	Fosfluconazole; Profluconazole; 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-yl dihydrogen phosphate; UK-2,985,043; UK 2985043; (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol phosphate (obsolete); Fluconazole phosphate prodrug
EINECS	Contact for details

Quality Control

Our Fosfluconazole is produced under strict quality management systems to ensure it meets the exacting standards required for pharmaceutical intermediates. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.