Description

Sbe7-β-Cd CAS NO 194615-04-8 is a chemically modified β-cyclodextrin derivative, specifically sulfobutyl ether β-cyclodextrin sodium salt, designed as a superior solubility enhancer and stabilizer for complex molecules. This high-purity excipient is critical for formulating poorly water-soluble active pharmaceutical ingredients (APIs), significantly improving their bioavailability and stability. It is an essential component for pharmaceutical manufacturers, research institutions, and specialty chemical producers focused on advanced drug delivery systems, analytical chemistry, and nanotechnology.

Application

• Pharmaceutical Formulations: As a key solubilizing and stabilizing agent in injectable, oral, and topical drug products to enhance the bioavailability of poorly soluble APIs.
• Drug Delivery Systems: Used in the development of controlled-release formulations, nanoparticles, liposomes, and inclusion complexes.
• Analytical Chemistry: Serves as a chiral selector in capillary electrophoresis and as a mobile phase additive in HPLC for the separation of enantiomers and isomers.
• Biotechnology & Biochemistry: Employed to stabilize proteins, enzymes, and other biological macromolecules in solution.
• Cosmetics & Personal Care: Acts as a carrier for fragrances and active ingredients in creams and lotions, improving their stability and skin penetration.
• Catalysis & Chemical Synthesis: Utilized as a phase-transfer catalyst or a reaction medium modifier in organic synthesis.

Basic Information

Product Name	Sbe7-β-Cd
CAS No.	194615-04-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sulfobutyl Ether β-Cyclodextrin Sodium Salt; Sulfobutylether-β-Cyclodextrin; SBE-β-CD; Captisol® (common trade name); β-Cyclodextrin Sulfobutyl Ether Sodium Salt; 6-O-α-D-Glucopyranosyl-β-cyclodextrin Sulfobutyl Ether Sodium Salt; SBE7-β-CD
EINECS	Contact for details

Quality Control

Our Sbe7-β-Cd is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, degree of substitution, residual solvents, and microbial limits. We adhere to cGMP guidelines and can support regulatory filings with relevant documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect product performance and stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Degree of Substitution (DS)	6.2 - 6.9
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Meets ICH limits
Heavy Metals	≤10 ppm
Bacterial Endotoxins	<0.5 EU/mg
Microbial Enumeration	Meets Ph. Eur. criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.