Description

2-Butynamide, n-[4-[(3-Bromophenyl)Amino]-6-Quinazolinyl]- is a specialized quinazoline derivative, a class of compounds renowned for their significant biological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other advanced small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors for oncology research.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic and cellular assays.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• API Development: Intermediate in the development and scale-up of Active Pharmaceutical Ingredients (APIs) with specific target profiles.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	2-Butynamide, n-[4-[(3-Bromophenyl)Amino]-6-Quinazolinyl]-
CAS No.	194423-06-8
Molecular Formula	C18H13BrN4O
Molecular Weight	381.23 g/mol
Synonyms	N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-butynamide; 4-[(3-Bromophenyl)amino]-6-quinazolinamine derivative; 2-Butynoic acid amide quinazoline derivative; 3-Bromophenyl-quinazolinyl butynamide; Kinase inhibitor intermediate 194423-06-8; Quinazoline-6-carboxamide derivative; Research compound 194423-06-8
EINECS	Contact for details

Quality Control

Every batch of 2-Butynamide, n-[4-[(3-Bromophenyl)Amino]-6-Quinazolinyl]- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.