Description

Benzoyl Chloride, 2-(Chloromethyl)-5-Fluoro- (9Ci) is a specialized fluorinated benzoyl chloride derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value proposition lies in its bifunctional reactivity, offering both an acid chloride and a chloromethyl group for sequential functionalization under controlled conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require precise molecular scaffolds for developing new active ingredients. Its unique structure facilitates the construction of complex molecules targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in advanced electronic and display materials.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for introducing aromatic and reactive chloromethyl functionalities into specialty polymers.
• Chemical Research & Development: A versatile reagent for exploring new fluorination strategies and constructing complex heterocyclic compounds in academic and industrial R&D labs.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, structurally defined fluorinated intermediates.

Basic Information

Product Name	Benzoyl Chloride, 2-(Chloromethyl)-5-Fluoro- (9Ci)
CAS No.	191934-72-2
Molecular Formula	C8H5Cl2FO
Molecular Weight	207.03 g/mol
Synonyms	2-(Chloromethyl)-5-fluorobenzoyl chloride; 5-Fluoro-2-(chloromethyl)benzoyl chloride; α,2-Dichloro-5-fluorotoluene; 2-Chloromethyl-5-fluorobenzoic acid chloride; (2-Chloromethyl-5-fluorophenyl)methanoyl chloride; Benzoyl chloride, 2-(chloromethyl)-5-fluoro-
EINECS	Contact for details

Quality Control

Our Benzoyl Chloride, 2-(Chloromethyl)-5-Fluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality systems are designed to support cGMP and ISO standards, making this material suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and classification as a strong acid/organic solvent, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.