Description

Benzoyl Chloride, 2-(Chloromethyl)-4-Fluoro- (9Ci) is a specialized fluorinated benzoyl chloride derivative, serving as a high-value chemical intermediate. Its core value proposition lies in its bifunctional reactivity, offering both an acid chloride and a chloromethyl group for sequential synthetic modifications. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to incorporate a fluorinated benzoyl moiety into complex molecules. Its precise structure enables the targeted synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atom enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic cores in electronic display and lighting technologies.
• Polymer Modification: Employed to introduce fluorinated benzoyl side chains into polymers, altering their surface properties, chemical resistance, and thermal stability.
• Custom Synthesis & Contract Research: A critical reagent for fine chemical manufacturers and CROs (Contract Research Organizations) developing proprietary compounds for clients.
• Chemical Research & Development: Fundamental reagent in academic and industrial labs exploring new fluorination strategies and heterocyclic chemistry.

Basic Information

Product Name	Benzoyl Chloride, 2-(Chloromethyl)-4-Fluoro- (9Ci)
CAS No.	191934-71-1
Molecular Formula	C8H5Cl2FO
Molecular Weight	207.03 g/mol
Synonyms	2-(Chloromethyl)-4-fluorobenzoyl chloride; 4-Fluoro-2-(chloromethyl)benzoyl chloride; α-Chloro-4-fluoro-o-toluoyl chloride; Benzoyl chloride, 2-(chloromethyl)-4-fluoro-; 191934-71-1; 2-Chloromethyl-4-fluorobenzoyl chloride
EINECS	Contact for details

Quality Control

Every batch of Benzoyl Chloride, 2-(Chloromethyl)-4-Fluoro- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our quality commitment supports compliance in cGMP and ISO-guided environments for pharmaceutical and industrial research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.