Description

3-Butyn-1-Yl Chloroformate 98 is a high-purity, reactive chloroformate ester derivative of 3-butyn-1-ol. This compound serves as a versatile and critical building block in organic synthesis, enabling the introduction of a terminal alkyne functional group protected as a chloroformate. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing molecules with alkyne handles for click chemistry (e.g., Huisgen cycloaddition).
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides where the alkyne moiety is a core structural element.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Material Science: Employed in surface modification and the development of advanced organic materials and coatings.
• Bioconjugation: Useful for modifying biomolecules, peptides, and proteins by introducing alkyne groups for subsequent labeling or attachment.
• Organic Synthesis Research: A valuable tool in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Product Name	3-Butyn-1-Yl Chloroformate 98
CAS No.	190774-49-3
Molecular Formula	C5H5ClO2
Molecular Weight	132.55 g/mol
Synonyms	3-Butynyl chloroformate; 3-Butyn-1-ol chloroformate; 4-Pentyn-1-yl chloroformate; Chloroformic acid 3-butyn-1-yl ester; But-3-yn-1-yl carbonochloridate; 190774-49-3; But-3-ynyl chloroformate
EINECS	Contact for details

Quality Control

Our 3-Butyn-1-Yl Chloroformate 98 is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chromatographic methods, to confirm identity and assay. Certificates of Analysis (COA) documenting purity and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.