Description

4-Piperidinecarbonyl Chloride (9Ci) is a versatile and highly reactive organic building block, crucial for the synthesis of complex molecules. Its primary value lies in its ability to introduce the piperidinecarbonyl moiety, a key structural feature in numerous pharmacologically active compounds. This intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, particularly for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting the central nervous system, as anesthetics, or analgesics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the piperidine scaffold contributes to biological activity.
• Fine Chemical Production: Serves as a key reagent in the multi-step synthesis of complex organic molecules for research and specialty chemical applications.
• Ligand and Catalyst Development: Employed in the creation of novel ligands and organocatalysts used in asymmetric synthesis and other advanced chemical transformations.
• Material Science Research: Utilized as a monomer or cross-linking agent in the development of specialty polymers with specific functional properties.

Basic Information

Product Name	4-Piperidinecarbonyl Chloride (9Ci)
CAS No.	190142-48-4
Molecular Formula	C6H10ClNO
Molecular Weight	147.60 g/mol
Synonyms	Isonipecotoyl Chloride; 4-(Chlorocarbonyl)piperidine; Piperidine-4-carbonyl chloride; 4-Piperidinecarboxylic acid chloride; 1-Piperidinecarbonyl chloride; 4-Carbamoylpiperidine hydrochloride (precursor related); Isonipecotic acid chloride
EINECS	Contact for details

Quality Control

Our 4-Piperidinecarbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.