Description

1H-Pyrazole-3-Carbonyl Chloride, 4-Chloro-1,5-Dimethyl- (9Ci) is a high-purity, reactive chemical intermediate belonging to the pyrazole class of heterocyclic compounds. Its value lies in its role as a versatile building block for synthesizing more complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and advanced functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyrazole core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, dyes, and photoactive materials for electronic and optoelectronic applications.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities producing bespoke compounds for clients.

Basic Information

Product Name	1H-Pyrazole-3-Carbonyl Chloride, 4-Chloro-1,5-Dimethyl- (9Ci)
CAS No.	189224-46-2
Molecular Formula	C6H6Cl2N2O
Molecular Weight	193.03 g/mol
Synonyms	4-Chloro-1,5-dimethyl-1H-pyrazole-3-carbonyl chloride; 4-Chloro-1,5-dimethylpyrazole-3-carbonyl chloride; 1,5-Dimethyl-4-chloro-1H-pyrazole-3-carbonyl chloride; 3-Carbonyl chloride-4-chloro-1,5-dimethylpyrazole; 189224-46-2; 4-Chloro-1,5-dimethyl-1H-pyrazole-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-3-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.