Description

2H-1-Benzopyran-2-Carbonyl Chloride,3,4-Dihydro-6-Hydroxy-2,5,7,8-Tetramethyl is a high-purity, functionalized benzopyran derivative that serves as a critical synthetic intermediate. Its value lies in its reactive carbonyl chloride group, which enables efficient coupling reactions for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting oxidative stress.
• Agrochemical Synthesis: Used in the research and development of new-generation crop protection agents and plant growth regulators.
• Nutraceutical & Cosmetic Ingredient Precursor: Serves as a synthetic precursor for tocopherol (Vitamin E) analogs and other antioxidant compounds used in high-value formulations.
• Material Science Research: Employed in the development of functional polymers and advanced organic materials with specific light-absorption or antioxidant properties.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Research: A versatile reagent for academic and industrial R&D focused on heterocyclic chemistry and the creation of complex organic molecules.

Basic Information

Product Name	2H-1-Benzopyran-2-Carbonyl Chloride,3,4-Dihydro-6-Hydroxy-2,5,7,8-Tetramethyl
CAS No.	188837-93-6
Molecular Formula	C15H17ClO3
Molecular Weight	280.75 g/mol
Synonyms	6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonyl chloride; Chroman-2-carbonyl chloride, 6-hydroxy-2,5,7,8-tetramethyl-; Trolox acid chloride; 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carbonyl chloride; 2H-1-Benzopyran-2-carbonyl chloride, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-; Trolox chloride; Tocopherol acid chloride derivative
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-2-Carbonyl Chloride,3,4-Dihydro-6-Hydroxy-2,5,7,8-Tetramethyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.