Description

5-Pyrimidinecarbonylchloride,2-Chloro-4-Methyl-(9Ci) is a high-purity, reactive heterocyclic building block essential for advanced organic synthesis. This compound matters as a key acyl chloride intermediate, enabling the efficient introduction of a functionalized pyrimidine moiety into target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the creation of molecular probes and labeled compounds for biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Pyrimidinecarbonylchloride,2-Chloro-4-Methyl-(9Ci)
CAS No.	188781-13-7
Molecular Formula	C7H4Cl2N2O
Molecular Weight	203.02 g/mol
Synonyms	2-Chloro-4-methylpyrimidine-5-carbonyl chloride; 2-Chloro-4-methyl-5-pyrimidinecarbonyl chloride; 2-Chloro-4-methylpyrimidine-5-carboxylic acid chloride; 5-Carboxy-2-chloro-4-methylpyrimidine chloride; (2-Chloro-4-methylpyrimidin-5-yl)carbonyl chloride; 188781-13-7; 2-Chloro-4-methyl-5-pyrimidinecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarbonylchloride,2-Chloro-4-Methyl-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.