Description

4-Bromo-2-Fluorobenzyl Alcohol is a versatile fluorinated and brominated benzyl alcohol derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional halogenated structure makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as drug discovery and the synthesis of liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides where the fluorine and bromine substituents enhance biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the creation of electron-transport or host materials for advanced OLED devices.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Protecting Group Chemistry: The benzyl alcohol functionality can be used in protecting group strategies or further functionalized to esters or ethers.
• Ligand Synthesis: Useful for preparing specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D settings.

Basic Information

Product Name	4-Bromo-2-Fluorobenzyl Alcohol
CAS No.	188582-62-9
Molecular Formula	C7H6BrFO
Molecular Weight	205.03 g/mol
Synonyms	(4-Bromo-2-fluorophenyl)methanol; 2-Fluoro-4-bromobenzyl alcohol; 4-Bromo-2-fluoro-benzenemethanol; 1-Bromo-4-(hydroxymethyl)-3-fluorobenzene; α-Hydroxy-4-bromo-2-fluorotoluene; 4-Bromo-2-fluorobenzylalcohol; 2-Fluoro-4-bromophenylmethanol; Benzenemethanol, 4-bromo-2-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorobenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements, from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to prevent oxidation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0% (Standard Grade)
Purity (GC)	≥97.5%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.