Description

5'-o-(Elaidoyl) 1-β-D-Arabinofuranosylcytosine CAS NO 188181-42-2 is a chemically modified nucleoside analog, specifically an elaidic acid ester derivative of cytarabine (ara-C). This compound is of significant interest in pharmaceutical research and development due to its potential as a prodrug, which can alter the pharmacokinetic profile and cellular uptake of the parent therapeutic agent. It is primarily utilized by researchers and manufacturers in the life sciences sector for advanced drug discovery programs, particularly in oncology and antiviral therapy development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic intermediate or prodrug candidate in the development of novel nucleoside-based therapeutics.
• Oncology Research: Investigated for its potential anti-cancer activity, leveraging the mechanism of cytarabine with modified bioavailability.
• Antiviral Agent Development: Used in research for creating new antiviral compounds targeting DNA viruses.
• Biochemical Research: Employed as a tool compound in studies of nucleoside metabolism, enzyme inhibition, and cell signaling pathways.
• Prodrug Strategy Studies: Acts as a model compound for studying esterification as a method to improve drug lipophilicity and membrane permeability.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5'-o-(Elaidoyl) 1-β-D-Arabinofuranosylcytosine
CAS No.	188181-42-2
Molecular Formula	C22H33N3O6
Molecular Weight	435.52 g/mol
Synonyms	1-β-D-Arabinofuranosylcytosine 5'-(9E)-octadecenoate; Cytarabine 5'-elaidate; 5'-O-[(9E)-Octadec-9-enoyl]cytarabine; 5'-O-Elaidoylcytarabine; ara-C 5'-elaidate; Elaidoyl Cytarabine; 5'-O-(trans-9-Octadecenoyl)cytosine β-D-arabinofuranoside; 188181-42-2
EINECS	Contact for details

Quality Control

Our 5'-o-(Elaidoyl) 1-β-D-Arabinofuranosylcytosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our commitment to quality assurance supports reliable and reproducible results for your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.