Description

Cyclopropanecarbonyl Chloride, 2,2-Dimethyl-3-(2-Methyl-1-Propenyl)-, (1R)- (9Ci) is a high-purity, chiral cyclopropane derivative featuring an acid chloride functional group and a prenyl-like side chain. This compound is a critical advanced pharmaceutical intermediate (API) for the synthesis of complex bioactive molecules, particularly in the development of novel therapeutic agents. It is essential for research and production in pharmaceutical and agrochemical sectors, where its unique stereochemistry and reactivity enable the construction of sophisticated target structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral active pharmaceutical ingredients (APIs) with potential antiviral, anticancer, or anti-inflammatory activity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane ring contributes to biological activity and stability.
• Chemical Research & Development: Serves as a versatile reagent in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Material Science Precursor: Potential use in synthesizing monomers or ligands for advanced polymeric or coordination complex materials.

Basic Information

Item	Details
Product Name	Cyclopropanecarbonyl Chloride, 2,2-Dimethyl-3-(2-Methyl-1-Propenyl)-, (1R)- (9Ci)
CAS No.	188023-87-2
Molecular Formula	C10H15ClO
Molecular Weight	186.68 g/mol
Synonyms	(1R)-2,2-Dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carbonyl chloride; (1R)-2,2-Dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarbonyl chloride; (R)-Chrysanthemic acid chloride derivative; (1R)-trans-Chrysanthemoyl chloride isomer; (1R,3R)-2,2-Dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carbonyl chloride; (+)-trans-2,2-Dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarbonyl chloride; Chiral cyclopropanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonyl Chloride, 2,2-Dimethyl-3-(2-Methyl-1-Propenyl)-, (1R)- (9Ci) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess, ensuring compliance with cGMP standards for pharmaceutical intermediates. Comprehensive Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its properties as a strong acid/organic solvent, hygroscopic (moisture-sensitive), and highly volatile nature, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from bases, oxidizing agents, and moisture sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.