Description

Carboxyamidotriazole Orotate is a rationally designed, non-cytotoxic small molecule inhibitor with significant research and development interest. This compound is valued for its potential to modulate specific cellular pathways, offering a unique mechanism of action for investigative applications. It is primarily utilized by pharmaceutical research organizations, biotechnology companies, and academic institutions engaged in advanced therapeutic discovery and biochemical mechanism studies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active investigational agent in preclinical studies for novel therapeutic targets.
• Biochemical Pathway Analysis: Used as a selective tool compound to study and validate specific intracellular signaling mechanisms in vitro.
• Oncology Research: Investigated for its potential anti-angiogenic and cytostatic properties in experimental cancer models.
• Academic Research: Employed in university and institutional labs for fundamental research in cell biology and pharmacology.
• Biotech Screening Libraries: Included in compound libraries for high-throughput screening (HTS) campaigns to identify new drug leads.
• Process Chemistry & Scale-up: Used as an intermediate or target molecule during the development and optimization of synthetic routes for pharmaceutical manufacturing.

Basic Information

Product Name	Carboxyamidotriazole Orotate
CAS No.	187739-60-2
Molecular Formula	C14H12N6O5
Molecular Weight	344.28 g/mol
Synonyms	Carboxyamidotriazole Orotate; CAI Orotate; L-651582 Orotate; NSC-609974 Orotate; 5-Amino-1-((2'-carbamoyl-1,1'-biphenyl-4-yl)methyl)-1H-1,2,3-triazole-4-carboxylic acid Orotate Salt; 1-[[4-(2-Carbamoylphenyl)phenyl]methyl]-5-amino-1H-1,2,3-triazole-4-carboxylic acid compound with 2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our Carboxyamidotriazole Orotate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.