Description

Ara-S CAS NO 187224-29-9 is a synthetic nucleoside analog of significant interest in pharmaceutical research and development. This compound is valued for its role as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery and process chemistry. Our supply ensures high purity and batch-to-batch consistency, critical for reliable experimental and manufacturing outcomes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Antiviral Agent Development: Investigated for its potential activity against DNA viruses in preclinical research.
• Oncology Research: Explored for its cytostatic or cytotoxic properties in cell-based assays and animal models.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Item	Detail
Product Name	Ara-S
CAS No.	187224-29-9
Molecular Formula	C9H11N3O5S
Molecular Weight	273.26 g/mol
Synonyms	4-Amino-1-((2R,3S,5R)-3-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 1-((2R,3S,5R)-3-Azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-aminopyrimidin-2(1H)-one; 3'-Azido-2',3'-dideoxy-5-fluorocytidine; Azidodideoxyfluorocytidine; Ara-S Nucleoside
EINECS	Contact for details

Quality Control

Every batch of Ara-S is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles as determined by HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.