Description

2-Fluoro-5-Iodobenzoyl Chloride is a high-purity, multi-functional aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 2-fluoro-5-iodobenzoyl moiety, a versatile scaffold for constructing complex molecules with tailored properties. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially in oncology and CNS-targeted therapies.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and pesticides with enhanced efficacy.
• Liquid Crystal & OLED Materials: Used in the production of specialty electronic materials and functional dyes.
• Peptide & Protein Modification: Acylating agent for modifying biomolecules in biochemical research and probe development.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki-Miyaura and Sonogashira couplings.
• Polymer Chemistry: Monomer for synthesizing specialty polymers with specific thermal or optical properties.

Basic Information

Item	Details
Product Name	2-Fluoro-5-Iodobenzoyl Chloride
CAS No.	186584-73-6
Molecular Formula	C7H3ClFIO
Molecular Weight	299.45 g/mol
Synonyms	5-Iodo-2-fluorobenzoyl chloride; 2-Fluoro-5-iodobenzoic acid chloride; Benzoic acid, 2-fluoro-5-iodo-, chloride; 186584-73-6; 2-Fluor-5-jodbenzoylchlorid; Chlorure de 2-fluoro-5-iodobenzoyle
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Iodobenzoyl Chloride is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency meet the stringent requirements of our global B2B clients. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent derivative, it should be kept away from moisture, strong bases, and oxidizing agents. Use appropriate corrosion-resistant storage materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0 - 103.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.