Description

N6-Boc-Adenosin-9-Yl Acetic Acid is a key Boc-protected adenosine derivative, serving as a crucial synthetic intermediate in advanced organic and medicinal chemistry. Its primary value lies in enabling the controlled synthesis and modification of nucleoside analogs, where the acid moiety provides a versatile handle for further conjugation. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing novel antiviral agents, anticancer drugs, and other therapeutic oligonucleotides.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Bioconjugation: Used to attach adenosine moieties to peptides, proteins, or other biomolecules via its carboxylic acid functional group.
• Probe Development: Serves as a precursor for creating labeled adenosine derivatives used in biochemical assays and diagnostic tools.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by allowing modifications at the N6 position of adenosine.
• Oligonucleotide Synthesis: Employed in the preparation of modified oligonucleotides for therapeutic and research applications.
• Chemical Biology: Facilitates the study of adenosine receptor interactions and nucleotide-mediated signaling pathways.

Basic Information

Product Name	N6-Boc-Adenosin-9-Yl Acetic Acid
CAS No.	186046-99-1
Molecular Formula	C₁₇H₂₃N₅O₇
Molecular Weight	409.40 g/mol
Synonyms	9-[(Carboxymethyl)amino]-N-[(1,1-dimethylethoxy)carbonyl]-9H-purin-6-amine; 6-[(tert-Butoxycarbonyl)amino]-9-(carboxymethyl)-9H-purine; N6-(tert-Butoxycarbonyl)adenosine-9-acetic acid; N6-Boc-9-carboxymethyladenine; Boc-Adenosine-9-CH2-COOH; Adenosine-9-acetic acid, N6-Boc-protected; 6-Boc-amino-9-carboxymethylpurine
EINECS	Contact for details

Quality Control

Our N6-Boc-Adenosin-9-Yl Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.