Description

(6-Benzhydryloxycarbonylamino-Purin-9-Yl)-Acetic Acid is a high-purity, protected nucleobase derivative designed for advanced pharmaceutical research and synthesis. This compound serves as a critical building block in the development of novel nucleoside analogs and other bioactive molecules, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of antiviral agents, anticancer drugs, and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of modified purine nucleosides and nucleotides for drug discovery programs.
• Antiviral Drug Research: Used in the development of novel antiviral compounds targeting viral polymerases and replication mechanisms.
• Oncology Research: Employed as a building block for creating purine-based analogs with potential anticancer activity.
• Medicinal Chemistry: Facilitates structure-activity relationship (SAR) studies by providing a protected amino-purine scaffold for further functionalization.
• Bioconjugation & Probe Development: The reactive acetic acid moiety allows for conjugation to other molecules, useful in creating biochemical probes.
• Process Chemistry & Scale-up: Serves as an intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs) under GMP-like conditions.

Basic Information

Product Name	(6-Benzhydryloxycarbonylamino-Purin-9-Yl)-Acetic Acid
CAS No.	186046-80-0
Molecular Formula	C21H19N5O4
Molecular Weight	405.41 g/mol
Synonyms	N-[(9H-Purin-6-yl)carbamoyl]-2-(diphenylmethoxy)acetamide; 2-[(Diphenylmethoxy)acetyl]-N-(9H-purin-6-yl)carboxamide; 6-[(Diphenylmethoxy)acetamido]purine; 6-(Benzhydryloxycarbonylamino)purin-9-ylacetic Acid; N6-[(Diphenylmethoxy)acetyl]adenine; Z-Ada-OH (where Z = benzhydryloxycarbonyl); (6-Z-Amino-Purin-9-Yl)-Acetic Acid
EINECS	Contact for details

Quality Control

Our (6-Benzhydryloxycarbonylamino-Purin-9-Yl)-Acetic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with customer requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.