Description

1-[3,5-Bis(Trifluoromethyl)Phenyl]Propan-1-Ol is a high-value fluorinated aromatic alcohol building block, prized for its unique electronic and steric properties imparted by the trifluoromethyl groups. This compound is critical for the synthesis of advanced materials and active pharmaceutical ingredients (APIs) where enhanced lipophilicity, metabolic stability, and bioavailability are required. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with superior performance characteristics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in antiviral, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved pesticidal activity and environmental persistence.
• Ligand & Catalyst Precursor: Serves as a precursor for sophisticated ligands in asymmetric catalysis and transition metal complexes used in fine chemical synthesis.
• Material Science Research: Employed in the development of fluorinated polymers, liquid crystals, and organic electronic materials for enhanced thermal and chemical stability.
• Chemical Biology Probe: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	1-[3,5-Bis(Trifluoromethyl)Phenyl]Propan-1-Ol
CAS No.	184888-50-4
Molecular Formula	C11H8F6O
Molecular Weight	270.17 g/mol
Synonyms	1-(3,5-Bis(trifluoromethyl)phenyl)-1-propanol; 3,5-Bis(trifluoromethyl)benzenepropanol; 1-Propanol, 1-[3,5-bis(trifluoromethyl)phenyl]-; α-Ethyl-3,5-bis(trifluoromethyl)benzenemethanol; 3,5-Bis(trifluoromethyl)phenyl propyl alcohol; (3,5-Bis(trifluoromethyl)phenyl)(ethyl)methanol; 1-(3,5-Di(trifluoromethyl)phenyl)propan-1-ol
EINECS	Contact for details

Quality Control

Our 1-[3,5-Bis(Trifluoromethyl)Phenyl]Propan-1-Ol is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.