Description

tert-Butyl n-(3-[(tert-Butyldimethylsilyl)Oxy]-2-Oxopropyl)Carbamate is a high-value, protected intermediate crucial for advanced organic synthesis. This compound matters because it provides a versatile handle for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and complex natural products.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for complex targets.
• Peptidomimetic Synthesis: Used in the preparation of peptide analogs and mimetics due to its protected amine and carbonyl functionalities.
• Protecting Group Strategy: The tert-butyldimethylsilyl (TBDMS) and Boc (tert-butoxycarbonyl) groups allow for selective protection and deprotection in complex synthetic routes.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, and insecticides requiring sophisticated molecular architectures.
• Academic & Contract Research: Essential reagent in university and CRO (Contract Research Organization) labs for methodological development and novel compound library generation.
• Custom Synthesis: Serves as a starting point for custom manufacturing of specialty chemicals and tailored intermediates for client-specific projects.

Basic Information

Product Name	tert-Butyl n-(3-[(tert-Butyldimethylsilyl)Oxy]-2-Oxopropyl)Carbamate
CAS No.	184429-84-3
Molecular Formula	C14H29NO4Si
Molecular Weight	303.48 g/mol
Synonyms	Boc-Aminoacetone TBDMS Ether; 3-[(tert-Butyldimethylsilyl)oxy]-2-oxopropylcarbamic acid tert-butyl ester; 1-[(tert-Butoxycarbonyl)amino]-3-[(tert-butyldimethylsilyl)oxy]propan-2-one; N-Boc-3-(tert-butyldimethylsilyloxy)-2-oxopropylamine; tert-Butyl [3-[(tert-butyldimethylsilyl)oxy]-2-oxopropyl]carbamate; (3-((tert-Butyldimethylsilyl)oxy)-2-oxopropyl)carbamic acid tert-butyl ester; N-Boc-3-TBDMSoxy-2-oxopropylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(3-[(tert-Butyldimethylsilyl)Oxy]-2-Oxopropyl)Carbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.