Description

Benzene, 2-Bromo-4-Fluoro-1-Isothiocyanato- (9Ci) is a specialized aromatic building block that integrates bromo, fluoro, and isothiocyanato functional groups on a benzene ring. This unique combination of halogens and a reactive isothiocyanate moiety makes it a high-value intermediate for constructing complex molecular architectures in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and materials science researchers for applications in medicinal chemistry, crop protection, and polymer synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for incorporating sulfur-containing pharmacophores.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the bromo and fluoro substituents enhance biological activity and stability.
• Ligand Synthesis: Employed in organometallic chemistry to create specialized ligands for catalysis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce specific properties into advanced polymeric materials.
• Chemical Biology Probes: Utilized to create isothiocyanate-based probes for labeling and studying biological targets.
• Organic Synthesis Building Block: Provides a versatile scaffold for further derivatization via the reactive isothiocyanate group.

Basic Information

Product Name	Benzene, 2-Bromo-4-Fluoro-1-Isothiocyanato- (9Ci)
CAS No.	183995-72-4
Molecular Formula	C7H3BrFNS
Molecular Weight	232.07 g/mol
Synonyms	2-Bromo-4-fluoro-1-isothiocyanatobenzene; 1-Bromo-3-fluoro-4-isothiocyanatobenzene; 2-Bromo-4-fluorophenyl isothiocyanate; Benzene, 1-bromo-3-fluoro-4-isothiocyanato-; 4-Fluoro-2-bromophenyl isothiocyanate; 183995-72-4; SCHEMBL21806227; BRN 29324365
EINECS	Contact for details

Quality Control

Every batch of Benzene, 2-Bromo-4-Fluoro-1-Isothiocyanato- (9Ci) is produced and analyzed under strict quality management protocols. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC-MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.