Description

Butanoyl Chloride, 4-Hydroxy- is a versatile bifunctional chemical intermediate, combining a reactive acid chloride group with a hydroxyl functionality. This unique structure makes it a valuable building block for the synthesis of more complex molecules, particularly in fine chemical and pharmaceutical manufacturing. It is essential for researchers and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce butanoyl moieties or create ester and amide linkages with additional hydroxyl handle for further modification.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a hydroxypbutyric acid derivative.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where its reactive groups allow for tailored molecular design.
• Polymer Modification: Serves as a monomer or grafting agent for creating functionalized polymers with specific properties like hydrophilicity or cross-linking sites.
• Fine Chemical Production: Employed in the manufacture of dyes, fragrances, and liquid crystals, where precise control over molecular structure is critical.
• Bioconjugation & Proteomics: Useful in biochemical research for labeling proteins or modifying peptides via its acid chloride group, with the hydroxyl group allowing for solubility tuning or further attachment.
• Material Science Research: Acts as a precursor for surface functionalization of nanomaterials and for developing novel organic-inorganic hybrid materials.

Basic Information

Item	Details
Product Name	Butanoyl Chloride, 4-Hydroxy-
CAS No.	183198-09-6
Molecular Formula	C4H7ClO2
Molecular Weight	122.55 g/mol
Synonyms	4-Hydroxybutanoyl chloride; γ-Hydroxybutyryl chloride; 4-Hydroxybutyric acid chloride; GHB chloride; 3-Carboxypropyl chloride; Tetrahydro-2-furanone chloride (derivative); 4-Hydroxybutanoic acid chloride
EINECS	Contact for details

Quality Control

Our Butanoyl Chloride, 4-Hydroxy- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency. We provide Certificates of Analysis (COA) with detailed specifications for identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and classification as a strong acid/organic solvent, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Acidity (Titration)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.