Description

1H-Benzimidazole-5-Carbonyl Chloride, 2,3-Dihydro-2-Oxo- (9Ci) is a key heterocyclic building block and reactive intermediate in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty chemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel benzimidazole-based drug candidates, including potential kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and development of new fungicides, herbicides, and plant growth regulators that leverage the benzimidazole scaffold.
• Material Science Research: Serves as a building block for creating specialized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes and molecular tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing high-value specialty chemicals for clients.

Basic Information

Product Name	1H-Benzimidazole-5-Carbonyl Chloride, 2,3-Dihydro-2-Oxo- (9Ci)
CAS No.	182952-97-2
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	2-Oxo-2,3-dihydro-1H-benzimidazole-5-carbonyl chloride; 1H-Benzimidazole-5-carbonyl chloride, 2,3-dihydro-2-oxo-; 2,3-Dihydro-2-oxo-1H-benzimidazole-5-carbonyl chloride; 5-(Chlorocarbonyl)-2,3-dihydro-2-oxobenzimidazole; 2-Oxobenzimidazoline-5-carbonyl chloride; 2-Oxo-1,2-dihydro-3H-benzimidazole-5-carbonyl chloride; 2,3-Dihydro-2-oxobenzimidazole-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 1H-Benzimidazole-5-Carbonyl Chloride, 2,3-Dihydro-2-Oxo- (9Ci) adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.