Description

1,14-Diazido-3,6,9,12-Tetraoxatetradecane is a specialized azide-functionalized polyethylene glycol derivative, serving as a critical bifunctional linker for advanced material synthesis. Its core value lies in enabling efficient, "click" chemistry-based cross-linking and functionalization under mild conditions, which is essential for creating tailored polymers and bioconjugates. This compound is particularly needed by R&D and production teams in the pharmaceutical, polymer science, and advanced materials sectors for applications ranging from drug delivery systems to specialty adhesives and coatings.

Application

• Polymer Cross-Linking Agent: Used in the synthesis of hydrogels, elastomers, and network polymers via copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC) reactions.
• Bioconjugation Linker: Facilitates the site-specific attachment of drugs, peptides, or fluorescent probes to antibodies, proteins, or nanoparticles for therapeutic and diagnostic applications.
• Surface Functionalization: Modifies material surfaces (e.g., silicon, gold, polymers) to introduce reactive azide groups for subsequent immobilization of biomolecules or catalysts.
• Dendrimer and Macromolecule Synthesis: Acts as a building block for constructing complex, branched macromolecular architectures with precise functionality.
• Energetic Materials Precursor: Serves as a component in the research and development of specialized propellants and explosives, leveraging its high nitrogen content.
• Click Chemistry Reagent: A key reagent in materials science and chemical biology for constructing diverse molecular libraries and functional materials efficiently.

Basic Information

Product Name	1,14-Diazido-3,6,9,12-Tetraoxatetradecane
CAS No.	182760-73-2
Molecular Formula	C10H20N6O4
Molecular Weight	288.30 g/mol
Synonyms	1,14-Diazido-3,6,9,12-tetraoxatetradecane; Tetraethylene Glycol Diazide; Azido-PEG4-azide; PEG4 Diazide; 3,6,9,12-Tetraoxatetradecane-1,14-diazide; 2,2'-(Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) diazide; Bis(2-(2-(2-azidoethoxy)ethoxy)ethyl) ether; 1-Azido-2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethane
EINECS	Contact for details

Quality Control

Our 1,14-Diazido-3,6,9,12-Tetraoxatetradecane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its azide functionality and sensitivity, keep away from heat, sparks, open flames, and strong reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.