Description

Fenoldopam Hydrochloride is a potent, selective dopamine D1 receptor agonist used as an active pharmaceutical ingredient (API). This compound is critical for its rapid-acting vasodilatory effects, making it a key agent in managing acute hypertensive emergencies. It is primarily required by pharmaceutical manufacturers and research institutions developing or producing cardiovascular medications and conducting related pharmacological studies. The product is supplied under stringent quality controls to ensure consistency and reliability for critical applications.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable formulations for the treatment of severe hypertension.
• Hospital Compounding: Used in hospital pharmacy settings for preparing urgent care medications for critical patients.
• Cardiovascular Research: A vital tool in preclinical and clinical research studying dopamine receptor mechanisms and renal hemodynamics.
• Reference Standard: Serves as a high-purity chemical reference standard for quality control laboratories in pharmaceutical analysis.
• Drug Development: Utilized in the R&D of new antihypertensive drugs and combination therapies.

Basic Information

Product Name	Fenoldopam Hydrochloride
CAS No.	181217-39-0
Molecular Formula	C16H16ClNO3 • HCl
Molecular Weight	342.21 g/mol
Synonyms	Fenoldopam HCl; 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol Hydrochloride; Corlopam; SKF-82526-J; (6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol) Hydrochloride; Fenoldopam Monohydrochloride
EINECS	Contact for details

Quality Control

Our Fenoldopam Hydrochloride is manufactured and tested to meet high-purity standards suitable for pharmaceutical applications. Quality assurance protocols are designed to ensure batch-to-batch consistency, identity, purity, and strength. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from tests including identification, assay, impurity profile, and residual solvents. Our quality system supports compliance with cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.