Description

4-(2-Thienyl)Benzoyl Chloride is a high-purity, reactive organic intermediate characterized by its benzoyl chloride core functionalized with a thiophene moiety. This compound is valued for its role as a versatile building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides where the thienyl-benzoyl structure imparts unique biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and photoactive materials for electronic applications.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and Industrial R&D: Utilized in research laboratories for methodological studies and exploring new chemical reactions involving acid chloride derivatives.

Basic Information

Product Name	4-(2-Thienyl)Benzoyl Chloride
CAS No.	181132-70-7
Molecular Formula	C11H7ClOS
Molecular Weight	222.69 g/mol
Synonyms	4-(Thiophen-2-yl)benzoyl chloride; 2-(4-Chlorocarbonylphenyl)thiophene; p-(2-Thienyl)benzoyl chloride; 4-(2-Thienyl)benzoic acid chloride; (4-Thiophen-2-yl-phenyl)-methanoyl chloride; Benzoyl chloride, 4-(2-thienyl)-; 181132-70-7
EINECS	Contact for details

Quality Control

Our 4-(2-Thienyl)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability, consistency, and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts vigorously with water, alcohols, and strong bases. Containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture and to maintain purity. Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.