Description

(S)-Sulconazole CAS NO 180185-78-8 is the single enantiomer of the broad-spectrum antifungal agent Sulconazole, offering enhanced specificity and potential for reduced side effects in pharmaceutical applications. This compound is critical for research and development focused on creating more targeted and efficacious antifungal therapies. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in chiral drug synthesis and advanced antifungal studies.

Application

• As a key chiral intermediate in the synthesis of advanced enantiopure antifungal active pharmaceutical ingredients (APIs).
• For research and development of novel topical and systemic antifungal medications with improved therapeutic profiles.
• In biochemical studies to investigate the structure-activity relationship (SAR) and mechanism of action of imidazole-class antifungals.
• As a reference standard in analytical laboratories for quality control and method development of chiral pharmaceutical products.
• For use in preclinical studies to evaluate the pharmacokinetics and pharmacodynamics of the (S)-enantiomer.

Basic Information

Product Name	(S)-Sulconazole
CAS No.	180185-78-8
Molecular Formula	C18H15Cl3N2S
Molecular Weight	397.75 g/mol
Synonyms	(S)-1-[2,4-Dichloro-β-[(4-chlorobenzyl)thio]phenethyl]imidazole; (S)-(-)-Sulconazole; (S)-Sulconazole Nitrate; (S)-Sulconazole free base; (S)-Sulconazole enantiomer; (S)-1-[2-[(4-Chlorophenyl)methylthio]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole; (S)-Sulconazole (base)
EINECS	Contact for details

Quality Control

Our (S)-Sulconazole is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and development purposes. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.