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(R)-Sulconazole CAS NO 180185-77-7
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CAS No.:180185-77-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R)-Sulconazole CAS NO 180185-77-7 is the single enantiomer form of the established antifungal agent Sulconazole, offering a more targeted pharmacological profile. This compound is critical for research and development focused on enhancing the efficacy and reducing the side effects of antifungal therapies. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in chiral drug development and advanced antifungal studies.
Application
- As a key chiral intermediate in the synthesis of novel, enantiomerically pure antifungal pharmaceutical agents.
- For use in pharmacological research to study the structure-activity relationship (SAR) and mechanism of action of imidazole-class antifungals.
- In analytical method development as a high-purity reference standard for chromatography (HPLC, GC) and spectroscopy.
- For biochemical research investigating fungal cell membrane biosynthesis and ergosterol inhibition.
- In the development of topical antifungal formulations where the specific (R)-enantiomer may offer improved therapeutic properties.
- As a building block in organic synthesis for creating more complex molecules with potential antimicrobial activity.
Basic Information
| Item | Details |
|---|---|
| Product Name | (R)-Sulconazole |
| CAS No. | 180185-77-7 |
| Molecular Formula | C18H15Cl3N2S |
| Molecular Weight | 397.75 g/mol |
| Synonyms | (R)-1-[2,4-Dichloro-β-[(4-chlorobenzyl)thio]phenethyl]imidazole; (R)-Sulconazole Nitrate; (R)-(-)-Sulconazole; (R)-Sulconazole free base; (R)-SCZ; (R)-Sulconazol; (R)-Sulconazole enantiomer |
| EINECS | Contact for details |
Quality Control
Our (R)-Sulconazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥98.0% |
| Chiral Purity (HPLC) | ≥99.0% (R)-enantiomer |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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