Description

(R)-Chlophedianol is the single enantiomer form of the antitussive agent chlophedianol, characterized by its specific stereochemistry at the chiral center. This high-purity chiral intermediate is critical for the research and development of enantiomerically pure pharmaceuticals, where the biological activity is often dependent on the absolute configuration. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on synthetic chemistry and drug discovery.

Application

• Key chiral building block for the synthesis of advanced pharmaceutical intermediates.
• Precursor in the research and development of enantioselective antitussive (cough suppressant) agents.
• Reference standard for analytical method development and quality control in chiral HPLC analysis.
• Starting material for pharmacological studies investigating stereospecific drug-receptor interactions.
• Intermediate in the preparation of deuterated or other isotopically labeled analogs for metabolic studies.
• Used in academic and industrial research exploring structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	(R)-Chlophedianol
CAS No.	179764-48-8
Molecular Formula	C12H18ClNO
Molecular Weight	227.73 g/mol
Synonyms	(R)-Chlophedianol; (R)-2-Chloro-α-(2-(dimethylamino)ethyl)benzhydrol; (R)-Clofedanol; (R)-ULO; Dexclofedanol; (R)-Tussiplegyl; (R)-1-(o-Chlorophenyl)-1-phenyl-3-dimethylaminopropan-1-ol; (R)-SKF-478
EINECS	Contact for details

Quality Control

Our (R)-Chlophedianol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet rigorous standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, chiral purity by HPLC, and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.