Description

Caspofungin Acetate is the acetate salt form of a semi-synthetic lipopeptide antifungal agent derived from a fermentation product of *Glarea lozoyensis*. This compound is a critical active pharmaceutical ingredient (API) valued for its potent and selective inhibition of β-(1,3)-D-glucan synthase, an enzyme essential for fungal cell wall synthesis. It is primarily required by pharmaceutical manufacturers and research institutions for the formulation of injectable antifungal medications and advanced clinical research into systemic fungal infections.

Application

• Pharmaceutical API: Core active ingredient in the manufacture of injectable antifungal drugs for the treatment of invasive candidiasis, aspergillosis, and other serious fungal infections.
• Hospital & Clinical Formulations: Used in compounding pharmacies and hospital settings for preparing specialized antifungal therapies, particularly for immunocompromised patients.
• Biomedical Research: Serves as a key reference standard and investigational tool in microbiology and pharmacology labs for studying fungal pathogenesis and resistance mechanisms.
• Drug Development: Employed in preclinical and clinical development stages for novel antifungal combination therapies and next-generation echinocandin analogs.
• Quality Control & Analytical Testing: Used as a certified reference material (CRM) in analytical laboratories for method validation, assay calibration, and impurity profiling of commercial drug products.

Basic Information

Product Name	Caspofungin Acetate
CAS No.	179463-17-3
Molecular Formula	C52H88N10O16 • xC2H4O2
Molecular Weight	1093.3 g/mol (for Caspofungin base)
Synonyms	Caspofungin Diacetate; MK-0991 Acetate; (1-((4R,5R)-4,5-Dihydroxy-N2-((4"-(pentyloxy)[1,1':4',1"-terphenyl]-4-yl)carbonyl)-L-ornithine)-5-((3R)-3-hydroxy-L-ornithine)pneumocandin B0 Acetate; Cancidas (Brand Name API); L-743,872 Acetate; Antifungal Lipopeptide Acetate
EINECS	Contact for details

Quality Control

Our Caspofungin Acetate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the stringent requirements for pharmaceutical active ingredients. Quality is assured through comprehensive testing including identity, purity, potency, and impurity profile analysis. A Certificate of Analysis (COA) is provided with each batch, detailing compliance with relevant specifications. Production can be aligned with cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccated environment after opening to maintain stability and potency. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0 %
Acetate Content	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Meets Ph. Eur./USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.