Description

Bortezomib CAS NO 179324-69-7 is a potent, selective, and reversible proteasome inhibitor, representing a critical class of therapeutic agents. It is primarily valued for its targeted mechanism of action in disrupting protein homeostasis within cells. This compound is essential for pharmaceutical research and development, particularly for manufacturers of oncology therapeutics and research institutions focused on hematological malignancies and solid tumors.

Application

• Active Pharmaceutical Ingredient (API) in the manufacture of injectable oncology drugs.
• Pharmaceutical Research & Development for studying proteasome function and intracellular signaling pathways.
• Preclinical and Clinical Studies targeting multiple myeloma, mantle cell lymphoma, and other cancers.
• Biochemical Research as a tool compound for investigating apoptosis and cell cycle regulation.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.

Basic Information

Product Name	Bortezomib
CAS No.	179324-69-7
Molecular Formula	C19H25BN4O4
Molecular Weight	384.24 g/mol
Synonyms	PS-341; LDP-341; MLN341; [(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; Velcade (Brand Name); Bortezomibum; Bortezomib (USAN, INN)
EINECS	Contact for details

Quality Control

Our Bortezomib is manufactured under strict quality systems to meet the rigorous standards required for pharmaceutical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant ICH guidelines and can supply material suitable for use as a Pharmaceutical Reference Standard or API intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.