Description

Benzenemethanol, α-Ethynyl-3-Fluoro-, (S)- (9Ci) is a high-purity, chiral fluorinated building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, combining a stereogenic center, a reactive ethynyl group, and a fluorine atom, enabling precise structural modifications. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the design and synthesis of advanced herbicides, fungicides, and insecticides where the fluorine atom and specific stereochemistry enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel fluorinated polymers and advanced organic materials with tailored properties.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, particularly in reactions involving alkynes and fluorinated aromatics.
• Peptidomimetics & Bio-conjugation: The ethynyl group allows for click chemistry applications, useful in creating peptide mimics and bioconjugates for drug discovery.

Basic Information

Item	Details
Product Name	Benzenemethanol, α-Ethynyl-3-Fluoro-, (S)- (9Ci)
CAS No.	179249-18-4
Molecular Formula	C9H7FO
Molecular Weight	150.15 g/mol
Synonyms	(S)-α-Ethynyl-3-fluorobenzyl alcohol; (S)-3-Fluoro-α-ethynylbenzenemethanol; (S)-1-(3-Fluorophenyl)-2-propyn-1-ol; (S)-3-Fluoro-α-ethynylbenzyl alcohol; (S)-1-Ethynyl-3-fluorobenzyl alcohol; (S)-FPEA alcohol; (S)-3-Fluoro phenyl ethynyl alcohol; (S)-FPEA
EINECS	Contact for details

Quality Control

Our Benzenemethanol, α-Ethynyl-3-Fluoro-, (S)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with high-purity standards for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.