Description

2(1H)-Pyrimidinone, 4-Amino-1-α-L-Ribofuranosyl- CAS NO 179239-81-7 is a high-purity nucleoside analog, a key building block in advanced pharmaceutical synthesis and biochemical research. This compound is critical for developing novel antiviral and anticancer therapeutics, offering researchers and manufacturers a reliable, high-quality intermediate. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of nucleoside-based active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside analog antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Antiviral Drug Development: Serves as a core scaffold for the research and development of therapeutics targeting viral polymerases.
• Oncology Research: Investigated for its potential incorporation into chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Pro-drug Synthesis: Utilized in the design and synthesis of pro-drugs to enhance bioavailability and targeting.
• Labeled Compound Production: Acts as a starting material for the synthesis of isotopically labeled (e.g., C13, N15) compounds for tracer studies.

Basic Information

Product Name	2(1H)-Pyrimidinone, 4-Amino-1-α-L-Ribofuranosyl-
CAS No.	179239-81-7
Molecular Formula	C9H13N3O5
Molecular Weight	243.22 g/mol
Synonyms	4-Amino-1-α-L-ribofuranosyl-2(1H)-pyrimidinone; 4-Amino-1-α-L-ribofuranosylpyrimidin-2(1H)-one; 4-Amino-1-(α-L-ribofuranosyl)-2(1H)-pyrimidinone; α-L-4-Aminocytidine; 1-(α-L-Ribofuranosyl)-4-aminopyrimidin-2(1H)-one; L-4-Aminocytidine; 4-Amino-1-β-L-ribofuranosyl-2(1H)-pyrimidinone (common alternate stereochemistry reference)
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyrimidinone, 4-Amino-1-α-L-Ribofuranosyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.