Description

2'-Deoxyuridine 5'-(Trihydrogen Imidodiphosphate) is a specialized nucleotide analog of significant interest in biochemical and pharmaceutical research. This compound serves as a crucial building block and research tool for studying enzyme mechanisms, particularly those involving DNA synthesis and repair. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in antiviral and anticancer drug discovery. The high-purity material is essential for ensuring the accuracy and reproducibility of sensitive biochemical assays.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies of DNA polymerases, nucleotidyltransferases, and kinases.
• Antiviral Drug Development: Serves as a precursor or analog in the research and synthesis of novel nucleoside-based antiviral agents.
• Diagnostic Reagents: Incorporated into enzymatic assay kits for the detection and quantification of specific enzyme activities in clinical and research settings.
• Cancer Research: Investigated for its potential role in modulating nucleotide metabolism pathways in cancer cells.
• Enzyme Mechanism Probes: Acts as a non-hydrolyzable or slow-turnover analog to trap enzymatic intermediates and elucidate reaction pathways.
• Academic Research: Fundamental tool for university and institutional labs studying nucleic acid biochemistry and molecular biology.

Basic Information

Product Name	2'-Deoxyuridine 5'-(Trihydrogen Imidodiphosphate)
CAS No.	178809-71-7
Molecular Formula	C9H15N3O12P2
Molecular Weight	443.18 g/mol
Synonyms	dUMP-PNP; 2'-Deoxyuridine-5'-imidodiphosphate; Deoxyuridine imidodiphosphate; dUMP-imidodiphosphate; Uridine, 2'-deoxy-, 5'-(P1-imino-P2-(5'-uridyl)) diphosphate; 5'-dUMP-PNP; Imidodiphosphate deoxyuridine derivative; PNP-dUMP
EINECS	Contact for details

Quality Control

Our 2'-Deoxyuridine 5'-(Trihydrogen Imidodiphosphate) is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.