Description

3,4,5-Trifluorobenzoyl Chloride is a high-purity fluorinated aromatic acid chloride serving as a critical building block in advanced organic synthesis. Its value lies in introducing the trifluoromethylbenzoyl moiety, which can significantly alter the physicochemical and biological properties of target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic core for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a building block for fluorinated compounds used in electronic displays.
• Polymer Chemistry: Employed in the production of specialty polymers and functional materials, including polyamides and polyesters with specific thermal and chemical resistance.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation and nucleophilic acyl substitution reactions to form amides, esters, and ketones.
• Chemical Research & Development: Fundamental material for exploring new chemical entities in medicinal and material science research.

Basic Information

Product Name	3,4,5-Trifluorobenzoyl Chloride
CAS No.	177787-26-7
Molecular Formula	C7H2ClF3O
Molecular Weight	194.54 g/mol
Synonyms	3,4,5-Trifluorobenzoic acid chloride; Benzoyl chloride, 3,4,5-trifluoro-; 3,4,5-Trifluorobenzoyl chloride; 3,4,5-Trifluorobenzoic acid chloride; 3,4,5-Trifluorobenzoylchloride; 3,4,5-Trifluoro-benzoyl chloride; 3,4,5-Trifluorobenzoic Acid Chloride; 3,4,5-Trifluorobenzoyl Chloride (177787-26-7)
EINECS	Contact for details

Quality Control

Our 3,4,5-Trifluorobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.