Description

Benzoyl Chloride, 4-Chloro-3-Fluoro- (9Ci) is a high-value, halogenated benzoyl chloride derivative serving as a critical building block in advanced organic synthesis. Its core value proposition lies in providing a reactive acid chloride handle for introducing the 4-chloro-3-fluorobenzoyl moiety, enabling the creation of complex molecules with tailored properties. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated benzoyl group to modulate bioavailability and receptor binding.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the chloro and fluoro substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating specialized aromatic cores in electronic and display materials.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and polyamides, imparting specific thermal and chemical resistance properties.
• Organic Synthesis & Research: A versatile reagent for peptide coupling reactions, esterifications, and the preparation of ketones via Friedel-Crafts acylation in academic and industrial R&D settings.

Basic Information

Product Name	Benzoyl Chloride, 4-Chloro-3-Fluoro- (9Ci)
CAS No.	177787-25-6
Molecular Formula	C7H3Cl2FO
Molecular Weight	192.99 g/mol
Synonyms	4-Chloro-3-fluorobenzoyl chloride; 3-Fluoro-4-chlorobenzoyl chloride; Benzoyl chloride, 4-chloro-3-fluoro-; (4-Chloro-3-fluorophenyl)carbonyl chloride; 4-Chloro-3-fluorobenzoic acid chloride
EINECS	Contact for details

Quality Control

Our production of Benzoyl Chloride, 4-Chloro-3-Fluoro- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analysis, including assay, identity confirmation, and impurity profiling. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.