Description

Di-tert-Butyl Chloromethylphosphonate is a high-purity organophosphorus compound used as a key synthetic intermediate. Its value lies in its role as a versatile building block for constructing complex molecules, particularly in pharmaceutical and agrochemical research and development. This product is essential for chemists and manufacturers in the life sciences sector who require reliable, high-quality intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing phosphonate or phosphate ester functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators where the phosphonate moiety is required for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for specialized phosphonate-based ligands used in asymmetric catalysis and metal complexation.
• Material Science Research: Employed in the development of novel polymers, flame retardants, and surface-modifying agents.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biochemical pathways and enzyme mechanisms.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for commercial production of fine chemicals.

Basic Information

Item	Details
Product Name	Di-tert-Butyl Chloromethylphosphonate
CAS No.	177348-28-6
Molecular Formula	C9H20ClO3P
Molecular Weight	242.68 g/mol
Synonyms	Chloromethylphosphonic Acid Di-tert-butyl Ester; Di-tert-butyl (Chloromethyl)phosphonate; Di-tert-butyl Chloromethylphosphonate; (Chloromethyl)phosphonic Acid Di-tert-butyl Ester; Di-tert-butylphosphonomethyl Chloride; t-Butyl Chloromethylphosphonate; DTBCMP; Chloromethyl Di-tert-butyl Phosphonate
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl Chloromethylphosphonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive analytical data, including HPLC, NMR, and GC analysis. Certificates of Analysis (COA) are available for every batch upon request, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.