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Carbamic Acid, n-[2-(2-Azidoethoxy)Ethyl]-, 1,1-Dimethylethyl Ester CAS NO 176220-30-7


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CAS No.:176220-30-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Carbamic Acid, n-[2-(2-Azidoethoxy)Ethyl]-, 1,1-Dimethylethyl Ester is a specialized organic compound featuring both a carbamate protecting group and an azide functional group, making it a valuable building block in advanced synthetic chemistry. This dual functionality is critical for applications requiring controlled reactivity and selective transformations, such as in the synthesis of complex pharmaceuticals and novel materials. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and bioconjugation sectors who require high-purity intermediates for click chemistry and peptide synthesis.

Application

  • Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those utilizing carbamate protecting group strategies.
  • Click Chemistry Reagent: The azide group enables efficient Huisgen 1,3-dipolar cycloaddition reactions with alkynes, facilitating the construction of triazole linkages in drug discovery and bioconjugation.
  • Peptide Synthesis: Used as a reagent for introducing protected amino or carbamate functionalities into peptide chains during solid-phase or solution-phase synthesis.
  • Polymer & Material Science: Acts as a monomer or cross-linking agent for creating functional polymers with tailored properties, such as hydrogels or smart materials.
  • Agrochemical Research: Employed in the development of novel herbicides, insecticides, or plant growth regulators that require specific carbamate derivatives.
  • Bioconjugation & Labeling: Facilitates the attachment of dyes, probes, or other molecules to proteins, antibodies, or nanoparticles for diagnostic and research applications.
  • Academic & Industrial R&D: A versatile tool for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name Carbamic Acid, n-[2-(2-Azidoethoxy)Ethyl]-, 1,1-Dimethylethyl Ester
CAS No. 176220-30-7
Molecular Formula C11H22N4O3
Molecular Weight 258.32 g/mol
Synonyms tert-Butyl N-[2-(2-azidoethoxy)ethyl]carbamate; 2-(2-Azidoethoxy)ethylcarbamic Acid tert-Butyl Ester; Boc-NH-PEG2-Azide; Azido-PEG2-t-butyl carbamate; N-(2-(2-Azidoethoxy)ethyl)-N-Boc-amine; t-Butyl (2-(2-azidoethoxy)ethyl)carbamate; 1-Boc-amino-3,6-dioxa-8-azidooctane; BOC-NH-PEG2-N3
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Quality Control

Our production of Carbamic Acid, n-[2-(2-Azidoethoxy)Ethyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to the presence of an azide functional group, standard safety precautions for azide compounds should be observed. Keep away from heat, sparks, open flames, and strong reducing agents.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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