Description

Ropivacaine-Ipr CAS NO 175888-75-2 is a high-purity pharmaceutical intermediate, specifically a key building block in the synthesis of Ropivacaine, a long-acting local anesthetic of the amino amide type. This compound is critical for ensuring the quality, efficacy, and safety of the final active pharmaceutical ingredient (API). It is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in the development and production of anesthetic formulations.

Application

• Primary Pharmaceutical Intermediate: Key synthetic precursor in the commercial production of Ropivacaine Hydrochloride API.
• Research & Development: Used in laboratories for developing new anesthetic compounds, studying structure-activity relationships (SAR), and process optimization.
• Process Chemistry: Employed in scaling up and validating synthetic routes for Ropivacaine under Good Manufacturing Practice (GMP) conditions.
• Analytical Reference Standard: Serves as a critical reference material for quality control (QC) and analytical method development (e.g., HPLC, GC) in API manufacturing.
• Custom Synthesis: Building block for creating novel derivatives and analogs of amide-type local anesthetics for patent-protected drug discovery.

Basic Information

Item	Detail
Product Name	Ropivacaine-Ipr
CAS No.	175888-75-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-Propyl-2',6'-pipecoloxylidide Impurity; Ropivacaine Related Compound Ipr; Ropivacaine Impurity Ipr; (S)-1-Propyl-2',6'-pipecoloxylidide intermediate; Ropivacaine Precursor; N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide intermediate; Ropivacaine Free Base Intermediate
EINECS	Contact for details

Quality Control

Our Ropivacaine-Ipr is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical intermediate applications. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with ICH guidelines and supports our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.