Description

5-Fluoro-2-Methylphenyl Isothiocyanate is a versatile and reactive organic building block, specifically an aryl isothiocyanate derivative. Its core value lies in its ability to serve as a key precursor for the synthesis of thiourea derivatives and heterocyclic compounds, which are essential scaffolds in modern chemical research and development. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly those targeting various enzyme families where the thiourea moiety is pharmacologically active.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive isothiocyanate group to create new active molecules.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation, labeling, or modifying proteins and peptides to study biological pathways.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialized polymers, resins, or coatings with unique properties.
• Ligand Synthesis: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry laboratories worldwide.

Basic Information

Item	Detail
Product Name	5-Fluoro-2-Methylphenyl Isothiocyanate
CAS No.	175205-39-7
Molecular Formula	C8H6FNS
Molecular Weight	167.20 g/mol
Synonyms	2-Methyl-5-fluorophenyl isothiocyanate; 5-Fluoro-o-tolyl isothiocyanate; (5-Fluoro-2-methylphenyl)isothiocyanate; 1-Fluoro-4-isothiocyanato-2-methylbenzene; 2-Fluoro-5-isothiocyanatotoluene; Isothiocyanic acid, 5-fluoro-2-methylphenyl ester
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methylphenyl Isothiocyanate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.