Description

2-(Trifluoromethoxy)Phenyl Isothiocyanate is a specialized aromatic isothiocyanate derivative, distinguished by the presence of a trifluoromethoxy substituent. This compound is a high-value synthetic intermediate prized for its reactivity, enabling the efficient introduction of the phenyl isothiocyanate moiety into target molecules. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, including the synthesis of potential drug candidates and biologically active molecules.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel heterocyclic compounds and active pharmaceutical ingredients (APIs) with potential therapeutic applications.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, leveraging the bioactivity of the isothiocyanate functional group.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation, labeling, or modifying proteins and peptides to study biological pathways.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialized polymers and advanced materials with unique properties.
• Ligand Synthesis: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(Trifluoromethoxy)Phenyl Isothiocyanate
CAS No.	175205-33-1
Molecular Formula	C8H4F3NOS
Molecular Weight	219.18 g/mol
Synonyms	1-Isothiocyanato-2-(trifluoromethoxy)benzene; 2-(Trifluoromethoxy)phenyl isothiocyanate; α,α,α-Trifluoro-o-anisyl isothiocyanate; (2-Trifluoromethoxyphenyl) isothiocyanate; 2-Trifluoromethoxyphenyl isothiocyanate; o-(Trifluoromethoxy)phenyl isothiocyanate; 1-Isothiocyanato-2-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethoxy)Phenyl Isothiocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques such as HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.