Description

1-(4-Isobutylphenyl)-3-[4-(Trifluoromethyl)Phenyl]Prop-2-En-1-One is a high-value, non-steroidal anti-inflammatory drug (NSAID) intermediate. This compound is critical for the synthesis of advanced pharmaceutical actives, offering a key structural motif for developing potent therapeutic agents. It is primarily sought by manufacturers in the pharmaceutical and fine chemical sectors for research and production of next-generation anti-inflammatory medications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel NSAIDs and other bioactive molecules.
• Organic Synthesis: Used as a key precursor in complex organic reactions, including cross-coupling and condensation reactions.
• Medicinal Chemistry Research: Employed in R&D for structure-activity relationship (SAR) studies and drug discovery programs targeting inflammation and pain.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring the chalcone or trifluoromethylphenyl structural units.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical laboratories.

Basic Information

Product Name	1-(4-Isobutylphenyl)-3-[4-(Trifluoromethyl)Phenyl]Prop-2-En-1-One
CAS No.	175205-28-4
Molecular Formula	C20H19F3O
Molecular Weight	332.36 g/mol
Synonyms	1-(4-Isobutylphenyl)-3-[4-(trifluoromethyl)phenyl]-2-propen-1-one; 3-[4-(Trifluoromethyl)phenyl]-1-[4-(2-methylpropyl)phenyl]prop-2-en-1-one; (E)-1-(4-Isobutylphenyl)-3-(4-(trifluoromethyl)phenyl)prop-2-en-1-one; Chalcone derivative; Trifluoromethyl Chalcone; Isobutylphenyl Trifluoromethyl Chalcone; NSAID Intermediate; CAS 175205-28-4
EINECS	Contact for details

Quality Control

Our 1-(4-Isobutylphenyl)-3-[4-(Trifluoromethyl)Phenyl]Prop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.