Description

4-[(4-Chlorophenyl)Sulfonyl]-3-Methylthiophene-2-Carbonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive carbonyl chloride and sulfonyl functional groups. This compound is critical for the synthesis of complex molecules, offering a versatile building block for constructing novel chemical architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its unique heterocyclic structure.
• Material Science: Serves as a precursor for specialty polymers or functional materials requiring sulfone and thiophene moieties.
• Organic Synthesis: Employed in academic and industrial R&D for constructing complex molecules via its reactive acid chloride group for amide or ester formation.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control in production.

Basic Information

Product Name	4-[(4-Chlorophenyl)Sulfonyl]-3-Methylthiophene-2-Carbonyl Chloride
CAS No.	175137-66-3
Molecular Formula	C12H8Cl2O3S2
Molecular Weight	335.22 g/mol
Synonyms	3-Methyl-4-[(4-chlorophenyl)sulfonyl]thiophene-2-carbonyl chloride; 4-(4-Chlorobenzenesulfonyl)-3-methylthiophene-2-carbonyl chloride; 2-Thiophenecarbonyl chloride, 4-[(4-chlorophenyl)sulfonyl]-3-methyl-; 175137-66-3; 4-(p-Chlorophenylsulfonyl)-3-methyl-2-thiophenecarbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-[(4-Chlorophenyl)Sulfonyl]-3-Methylthiophene-2-Carbonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee compliance with your research and manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.