Description

5-Chloro-4-Methoxythiophene-3-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters because it serves as a critical building block for constructing complex heterocyclic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those containing functionalized thiophene scaffolds.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science Research: Used in the creation of organic semiconductors, conductive polymers, and other specialty electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.
• Academic & Industrial R&D: Fundamental reagent for methodological development and exploring new chemical reactions in heterocyclic chemistry.

Basic Information

Product Name	5-Chloro-4-Methoxythiophene-3-Carbonyl Chloride
CAS No.	175137-49-2
Molecular Formula	C7H4Cl2O2S
Molecular Weight	223.08 g/mol
Synonyms	5-Chloro-4-methoxy-3-thiophenecarbonyl chloride; 3-Thiophenecarbonyl chloride, 5-chloro-4-methoxy-; 5-Chloro-4-methoxythiophene-3-carboxylic acid chloride; 4-Methoxy-5-chlorothiophene-3-carbonyl chloride; 175137-49-2; 5-Chloro-4-methoxy-thiophene-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-4-Methoxythiophene-3-Carbonyl Chloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.