Description

1-(4-Nitrophenyl)-5-(Trifluoromethyl)Pyrazole-4-Carbonyl Chloride is a high-value, multi-functional chemical intermediate designed for advanced synthesis. Its core value lies in its reactive carbonyl chloride group and unique trifluoromethylpyrazole scaffold, enabling the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly those targeting inflammation, oncology, and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating specialized polymers or ligands with tailored electronic and binding properties.
• Chemical Biology Probes: Employed in the development of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(4-Nitrophenyl)-5-(Trifluoromethyl)Pyrazole-4-Carbonyl Chloride
CAS No.	175137-36-7
Molecular Formula	C11H5ClF3N3O3
Molecular Weight	319.62 g/mol
Synonyms	4-Carbonyl Chloride-1-(4-nitrophenyl)-5-(trifluoromethyl)pyrazole; 1-(p-Nitrophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carbonyl chloride; 5-(Trifluoromethyl)-1-(4-nitrophenyl)-1H-pyrazole-4-carbonyl chloride; 1-(4-Nitrophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carbonyl chloride; Pyrazole-4-carbonyl chloride, 1-(4-nitrophenyl)-5-(trifluoromethyl)-; 175137-36-7; 1H-Pyrazole-4-carbonyl chloride, 1-(4-nitrophenyl)-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 1-(4-Nitrophenyl)-5-(Trifluoromethyl)Pyrazole-4-Carbonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.