Description

2-(4-Chlorophenyl)-3-(Trifluoromethyl)Pyrazole-4-Carbonyl Chloride is a high-value, reactive chemical intermediate essential for constructing complex molecular architectures. Its core value lies in the versatile pyrazole-carbonyl chloride scaffold, which enables efficient synthesis of amides, esters, and other derivatives under mild conditions. This compound is critically needed by R&D and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients, particularly those targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in drug discovery programs for anti-inflammatory, antiviral, or anticancer agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging the bioactivity of the pyrazole and trifluoromethyl groups.
• Material Science Research: Serves as a precursor for creating specialized polymers, ligands, or functional materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) producing custom compounds for client projects.
• Academic & Industrial R&D: Utilized in research laboratories for method development and exploring new chemical reactions involving acid chlorides and heterocycles.

Basic Information

Product Name	2-(4-Chlorophenyl)-3-(Trifluoromethyl)Pyrazole-4-Carbonyl Chloride
CAS No.	175137-19-6
Molecular Formula	C11H5Cl2F3N2O
Molecular Weight	309.07 g/mol
Synonyms	4-Chlorocarbonyl-2-(4-chlorophenyl)-3-(trifluoromethyl)pyrazole; 1H-Pyrazole-4-carbonyl chloride, 2-(4-chlorophenyl)-3-(trifluoromethyl)-; 2-(p-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazole-4-carbonyl chloride; 175137-19-6; Pyrazole-4-carbonyl chloride derivative
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Chlorophenyl)-3-(Trifluoromethyl)Pyrazole-4-Carbonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from moisture, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.