Description

2,2,5,7-Tetramethyl-1-Oxoindane-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate featuring a sterically hindered indane core. This compound matters for its role as a critical building block in the synthesis of complex organic molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those with sterically demanding structures.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides requiring specific, hindered molecular frameworks.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, dyes, and functional materials.
• Organic Synthesis Reagent: Employed in academic and industrial research for introducing the tetramethyl-oxoindane carbonyl moiety into target molecules via acyl chloride chemistry.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers with unique thermal or optical properties.
• Ligand and Catalyst Development: Useful for constructing complex, chiral ligands used in asymmetric catalysis.

Basic Information

Product Name	2,2,5,7-Tetramethyl-1-Oxoindane-4-Carbonyl Chloride
CAS No.	175136-59-1
Molecular Formula	C15H17ClO2
Molecular Weight	264.75 g/mol
Synonyms	4-(Chlorocarbonyl)-2,2,5,7-tetramethyl-1-indanone; 1-Indanone, 4-(chlorocarbonyl)-2,2,5,7-tetramethyl-; 2,2,5,7-Tetramethyl-1-indanone-4-carbonyl chloride; 4-Carboxy-2,2,5,7-tetramethyl-1-indanone chloride; Tetramethyloxoindanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 2,2,5,7-Tetramethyl-1-Oxoindane-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.