Description

3-(2-Chloro-3,4-Dimethoxyphenyl)Prop-2-Enoyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound is valued for its role as a key building block in the creation of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its specific aromatic substitution pattern.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, where the chlorodimethoxyphenyl moiety can impart specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of advanced polymers and functional organic materials with tailored electronic or optical properties.
• Custom Synthesis and Contract Manufacturing: A vital component for fine chemical manufacturers offering bespoke synthesis services for clients in life sciences.

Basic Information

Product Name	3-(2-Chloro-3,4-Dimethoxyphenyl)Prop-2-Enoyl Chloride
CAS No.	175136-00-2
Molecular Formula	C11H10Cl2O3
Molecular Weight	261.10 g/mol
Synonyms	2-Chloro-3,4-dimethoxycinnamoyl chloride; (E)-3-(2-Chloro-3,4-dimethoxyphenyl)acryloyl chloride; 3-(2-Chloro-3,4-dimethoxyphenyl)acryloyl chloride; trans-3-(2-Chloro-3,4-dimethoxyphenyl)prop-2-enoyl chloride; 2-Chloro-3,4-dimethoxy-trans-cinnamoyl chloride; Cinnamoyl chloride, 2-chloro-3,4-dimethoxy-; (2E)-3-(2-Chloro-3,4-dimethoxyphenyl)prop-2-enoyl chloride
EINECS	Contact for details

Quality Control

Our production of 3-(2-Chloro-3,4-Dimethoxyphenyl)Prop-2-Enoyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Every lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive acid chloride nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.